SERPINF1, serpin family F member 1

SERPINF1, serpin family F member 1

• This gene encodes a member of the serpin family that does not display the serine protease inhibitory activity shown by many of the other serpin proteins. The encoded protein is secreted and strongly inhibits angiogenesis. In addition, this protein is a neurotrophic factor involved in neuronal differentiation in retinoblastoma cells. Mutations in this gene were found in individuals with osteogenesis imperfecta, type VI. [provided by RefSeq, Aug 2016]

• Gene Synonyms (pigment epithelium-derived factor, alpha-2 antiplasmin, cell proliferation-inducing gene 35 protein, serine (or cysteine) proteinase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1, serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1, testis tissue sperm-binding protein Li 70n, EPC-1, OI12, OI6, PEDF, PIG35,)
• NCBI Gene ID: 5176
• Species: Homo sapiens (Human)
• UNIPROT ID#>>A0A140VKF3
  UNIPROT ID#>>P36955
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

serpin family F member 1 interacts with:

• EPM2A interacting protein 1
  impact RWD domain protein
  kelch like family member 8
  L3MBTL histone methyl-lysine binding protein 2
  NEDD4 like E3 ubiquitin protein ligase
  patatin like phospholipase domain containing 2
  protein tyrosine phosphatase non-receptor type 11
  small glutamine rich tetratricopeptide repeat containing beta
  transmembrane protein 25
  tubulin alpha 4a

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.