AICDA, activation induced cytidine deaminase

AICDA, activation induced cytidine deaminase

• This gene encodes a RNA-editing deaminase that is a member of the cytidine deaminase family. The protein is involved in somatic hypermutation, gene conversion, and class-switch recombination of immunoglobulin genes. Defects in this gene are the cause of autosomal recessive hyper-IgM immunodeficiency syndrome type 2 (HIGM2). [provided by RefSeq, Feb 2009]

• Gene Synonyms (AID, ARP2, CDA2, HEL-S-284, HIGM2, single-stranded DNA cytosine deaminase, cytidine aminohydrolase, epididymis secretory protein Li 284, integrated into Burkitt's lymphoma cell line Ramos,)
• NCBI Gene ID: 57379
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q7Z599
  UNIPROT ID#>>Q6QJ80
  UNIPROT ID#>>Q546Y9
  UNIPROT ID#>>Q9GZX7
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

activation induced cytidine deaminase interacts with:

• activation induced cytidine deaminase
  exosome component 6
  HERPUD family member 2
  zinc finger MIZ-type containing 2

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.