PHLDA2, pleckstrin homology like domain family A member 2

PHLDA2, pleckstrin homology like domain family A member 2

• This gene is located in a cluster of imprinted genes on chromosome 11p15.5, which is considered to be an important tumor suppressor gene region. Alterations in this region may be associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocortical carcinoma, and lung, ovarian, and breast cancer. This gene has been shown to be imprinted, with preferential expression from the maternal allele in placenta and liver. [provided by RefSeq, Oct 2010]

• Gene Synonyms (pleckstrin homology-like domain family A member 2, beckwith-Wiedemann syndrome chromosomal region 1 candidate gene C protein, imprinted in placenta and liver protein, p17-BWR1C, p17-Beckwith-Wiedemann region 1 C, p17-Beckwith-Wiedemann region 1C, tumor suppressing subchromosomal transferable fragment cDNA 3, tumor suppressing subtransferable candidate 3, tumor-suppressing subchromosomal transferable fragment candidate gene 3 protein, tumor-supressing STF cDNA 3, BRW1C, BWR1C, HLDA2, IPL, TSSC3,)
• NCBI Gene ID: 7262
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q53GA4
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

pleckstrin homology like domain family A member 2 interacts with:

• centromere protein E
  FCH and mu domain containing endocytic adaptor 1
  OTU deubiquitinase, ubiquitin aldehyde binding 2
  potassium channel tetramerisation domain containing 5
  RAN binding protein 9
  SSX family member 2B
  SUN domain containing ossification factor

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.