PCGF6, polycomb group ring finger 6

PCGF6, polycomb group ring finger 6

• The protein encoded by this gene contains a RING finger motif, which is most closely related to those of polycomb group (PcG) proteins RNF110/MEL-18 and BMI1. PcG proteins are known to form protein complexes and function as transcription repressors. This protein has been shown to interact with some PcG proteins and act as a transcription repressor. The activity of this protein is found to be regulated by cell cycle dependent phosphorylation. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]

• Gene Synonyms (polycomb group RING finger protein 6, Mel18 and Bmi1-like RING finger protein, ring finger protein 134, MBLR, RNF134,)
• NCBI Gene ID: 84108
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q9BYE7
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

polycomb group ring finger 6 interacts with:

• centrosomal protein 170B
  centrosomal protein 78
  coronin 6
  DEAD-box helicase 51
  kelch-like 22
  L3MBTL2 polycomb repressive complex 1 subunit
  MAGE family member E2
  polycomb group ring finger 6
  RPTOR independent companion of MTOR complex 2
  ubiquitin conjugating enzyme E2 U
  WBP2 N-terminal like
  zinc finger protein 526
  zinc finger protein 644

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.