TGFBRAP1, transforming growth factor beta receptor associated protein 1

TGFBRAP1, transforming growth factor beta receptor associated protein 1

• This gene encodes a protein that binds to transforming growth factor-beta (TGF-beta) receptors and plays a role in TGF-beta signaling. The encoded protein acts as a chaprone in signaling downstream of TGF-beta. It is involved in signal-dependent association with SMAD4. The protein is also a component of mammalian CORVET, a multisubunit tethering protein complex that is involved in fusion of early endosomes. [provided by RefSeq, Jun 2016]

• Gene Synonyms (transforming growth factor-beta receptor-associated protein 1, TGF-beta receptor-associated protein 1, VPS3 CORVET complex subunit, TRAP-1, TRAP1, VPS3,)
• NCBI Gene ID: 9392
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q8WUH2
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

transforming growth factor beta receptor associated protein 1 interacts with:

• ADP ribosylation factor GTPase activating protein 1
  base methyltransferase of 25S rRNA 2 homolog
  ciliary rootlet coiled-coil, rootletin
  isochorismatase domain containing 2
  nuclear receptor binding factor 2
  proteasome 26S subunit, non-ATPase 14
  ring finger protein 38
  transmembrane protein 266
  vir like m6A methyltransferase associated
  VPS11 core subunit of CORVET and HOPS complexes
  VPS16 core subunit of CORVET and HOPS complexes
  VPS18 core subunit of CORVET and HOPS complexes
  VPS33A core subunit of CORVET and HOPS complexes
  VPS41 HOPS complex subunit
  VPS41 subunit of HOPS complex
  VPS8 subunit of CORVET complex

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.