TMEM59, transmembrane protein 59

TMEM59, transmembrane protein 59

• This gene encodes a protein shown to regulate autophagy in response to bacterial infection. This protein may also regulate the retention of amyloid precursor protein (APP) in the Golgi apparatus through its control of APP glycosylation. Overexpression of this protein has been found to promote apoptosis in a glioma cell line. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2015]

• Gene Synonyms (transmembrane protein 59, dendritic cell factor 1, liver membrane-bound protein, C1orf8, DCF1, HSPC001, PRO195, UNQ169,)
• NCBI Gene ID: 9528
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q5T703
  UNIPROT ID#>>Q9BXS4
  UNIPROT ID#>>D3DQ48
  UNIPROT ID#>>Q5T6Z8
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

transmembrane protein 59 interacts with:

• autophagy related 16 like 1
  cullin 7
  ERBB receptor feedback inhibitor 1
  integrin alpha FG-GAP repeat containing 1
  interleukin 20 receptor subunit beta
  limb development membrane protein 1 like
  protein kinase D2
  transmembrane protein 30A
  tRNA-yW synthesizing protein 1 homolog

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.