MRC2, mannose receptor C type 2

MRC2, mannose receptor C type 2

• This gene encodes a member of the mannose receptor family of proteins that contain a fibronectin type II domain and multiple C-type lectin-like domains. The encoded protein plays a role in extracellular matrix remodeling by mediating the internalization and lysosomal degradation of collagen ligands. Expression of this gene may play a role in the tumorigenesis and metastasis of several malignancies including breast cancer, gliomas and metastatic bone disease. [provided by RefSeq, Feb 2012]

• Gene Synonyms (C-type mannose receptor 2, C-type lectin domain family 13 member E, UPAR-associated protein, endocytic receptor (macrophage mannose receptor family), endocytic receptor 180, macrophage mannose receptor 2, urokinase-type plasminogen activator receptor-associated protein, CD280, CLEC13E, ENDO180, UPARAP,)
• NCBI Gene ID: 9902
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q9UBG0
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

mannose receptor C type 2 interacts with:

• BRMS1 transcriptional repressor and anoikis regulator
  F-box protein 6
  lectin, mannose binding 2 like
  lysozyme like 2
  metadherin
  nudE neurodevelopment protein 1 like 1
  partner and localizer of BRCA2
  secretoglobin family 1D member 1
  TAFA chemokine like family member 3
  TAFA chemokine like family member 4
  TRAF family member associated NFKB activator
  vir like m6A methyltransferase associated

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.