PIGK, phosphatidylinositol glycan anchor biosynthesis class K

PIGK, phosphatidylinositol glycan anchor biosynthesis class K

• This gene encodes a member of the cysteine protease family C13 that is involved in glycosylphosphatidylinositol (GPI)-anchor biosynthesis. The GPI-anchor is a glycolipid found on many blood cells and serves to anchor proteins to the cell surface. This protein is a member of the multisubunit enzyme, GPI transamidase and is thought to be its enzymatic component. GPI transamidase mediates GPI anchoring in the endoplasmic reticulum, by catalyzing the transfer of fully assembled GPI units to proteins. [provided by RefSeq, Jul 2008]

• Gene Synonyms (GPI-anchor transamidase, GPI transamidase subunit, GPI8 homolog, PIG-K, phosphatidylinositol glycan, class K, phosphatidylinositol-glycan biosynthesis class K protein, GPI8, NEDHCAS,)
• NCBI Gene ID: 10026
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q92643
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

phosphatidylinositol glycan anchor biosynthesis class K interacts with:

• F-box protein 6
  LY6/PLAUR domain containing 3
  phosphatidylinositol glycan anchor biosynthesis class S
  phosphatidylinositol glycan anchor biosynthesis class T
  phosphatidylinositol glycan anchor biosynthesis class U
  pleckstrin homology domain containing A4
  serine protease 50
  solute carrier family 15 member 3
  tectonic family member 3
  tripartite motif containing 28
  UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3
  UL16 binding protein 2
  unc-93 homolog B1, TLR signaling regulator

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