USH1C, USH1 protein network component harmonin

USH1C, USH1 protein network component harmonin

• This gene encodes a scaffold protein that functions in the assembly of Usher protein complexes. The protein contains PDZ domains, a coiled-coil region with a bipartite nuclear localization signal and a PEST degradation sequence. Defects in this gene are the cause of Usher syndrome type 1C and non-syndromic sensorineural deafness autosomal recessive type 18. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009]

• Gene Synonyms (harmonin, Usher syndrome 1C (autosomal recessive, severe), antigen NY-CO-38/NY-CO-37, autoimmune enteropathy-related antigen AIE-75, renal carcinoma antigen NY-REN-3, usher syndrome type-1C protein, AIE-75, DFNB18, DFNB18A, NY-CO-37, NY-CO-38, PDZ-45, PDZ-73, PDZ-73/NY-CO-38, PDZ73, PDZD7C, ush1cpst,)
• NCBI Gene ID: 10083
• Species: Homo sapiens (Human)
• UNIPROT ID#>>A0A0S2Z4V1
  UNIPROT ID#>>A0A0S2Z4U9
  UNIPROT ID#>>Q9Y6N9
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

USH1 protein network component harmonin interacts with:

• ankyrin repeat and sterile alpha motif domain containing 4B
  cadherin related 23
  COP9 signalosome subunit 8
  enkurin domain containing 1
  F-box protein 7
  LTV1 ribosome biogenesis factor
  mirror-image polydactyly 1
  protocadherin beta 12
  serum amyloid A like 1
  tubulin beta 1 class VI
  ubiquitin specific peptidase 46
  USH1 protein network component harmonin
  USH1 protein network component harmonin binding protein 1
  USH1 protein network component sans
  WD repeat domain 20
  WD repeat domain 48
  WD repeat domain 61

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.