FARP1, FERM, ARH/RhoGEF and pleckstrin domain protein 1

FARP1, FERM, ARH/RhoGEF and pleckstrin domain protein 1

• This gene encodes a protein containing a FERM (4.2, exrin, radixin, moesin) domain, a Dbl homology domain, and two pleckstrin homology domains. These domains are found in guanine nucleotide exchange factors and proteins that link the cytoskeleton to the cell membrane. The encoded protein functions in neurons to promote dendritic growth. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2013]

• Gene Synonyms (FERM, ARHGEF and pleckstrin domain-containing protein 1, FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived), FERM, RhoGEF and pleckstrin domain-containing protein 1, PH domain-containing family C member 2, chondrocyte-derived ezrin-like protein, pleckstrin homology domain-containing family C member 2, protein phosphatase 1, regulatory subunit 75, CDEP, FARP1-IT1, PLEKHC2, PPP1R75,)
• NCBI Gene ID: 10160
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q9Y4F1
  UNIPROT ID#>>C9JME2
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

FERM, ARH/RhoGEF and pleckstrin domain protein 1 interacts with:

• coronin, actin binding protein 1C
  DDB1 and CUL4 associated factor 8
  filamin, beta
  flotillin 1
  flotillin 2
  GAR1 ribonucleoprotein
  gem nuclear organelle associated protein 7
  hook microtubule tethering protein 1
  myosin, heavy polypeptide 10, non-muscle
  myosin, heavy polypeptide 9, non-muscle
  PIH1 domain containing 1
  pleckstrin homology domain containing A4
  poly(rC) binding protein 2
  protein arginine N-methyltransferase 5
  protein kinase, cAMP dependent regulatory, type II alpha
  receptor interacting serine/threonine kinase 4
  synaptopodin
  trafficking protein particle complex 8
  USO1 vesicle docking factor

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.