ALG3, ALG3 alpha-1,3- mannosyltransferase

ALG3, ALG3 alpha-1,3- mannosyltransferase

• This gene encodes a member of the ALG3 family. The encoded protein catalyses the addition of the first dol-P-Man derived mannose in an alpha 1,3 linkage to Man5GlcNAc2-PP-Dol. Defects in this gene have been associated with congenital disorder of glycosylation type Id (CDG-Id) characterized by abnormal N-glycosylation. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2008]

• Gene Synonyms (dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase, Not56-like protein, asparagine-linked glycosylation 3 homolog (S. cerevisiae, alpha-1,3-mannosyltransferase), asparagine-linked glycosylation 3 homolog (yeast, alpha-1,3-mannosyltransferase), asparagine-linked glycosylation 3, alpha-1,3- mannosyltransferase homolog, asparagine-linked glycosylation protein 3 homolog, carbohydrate deficient glycoprotein syndrome type IV, dol-P-Man-dependent alpha(1-3)-mannosyltransferase, dolichyl-P-Man:Man(5)GlcNAc(2)-PP-dolichyl mannosyltransferase, dolichyl-phosphate-mannose--glycolipid alpha-mannosyltransferase, CDG1D, CDGS4, CDGS6, D16Ertd36e, NOT56L, Not56, not,)
• NCBI Gene ID: 10195
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q92685
  UNIPROT ID#>>C9J7S5
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

ALG3 alpha-1,3- mannosyltransferase interacts with:

• ADP ribosylation factor like GTPase 13B
  cAMP responsive element binding protein 3
  claudin domain containing 1
  ERGIC and golgi 3
  kelch like family member 14
  serine rich single-pass membrane protein 1
  stress associated endoplasmic reticulum protein 1
  tectonic family member 2
  tectonic family member 3
  testis specific 10 interacting protein
  transmembrane protein 52B

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.