- Gene Overview
- Interaction Network
- Sequence Verification
SEMA3A, semaphorin 3A
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This gene is a member of the semaphorin family and encodes a protein with an Ig-like C2-type (immunoglobulin-like) domain, a PSI domain and a Sema domain. This secreted protein can function as either a chemorepulsive agent, inhibiting axonal outgrowth, or as a chemoattractive agent, stimulating the growth of apical dendrites. In both cases, the protein is vital for normal neuronal pattern development. Increased expression of this protein is associated with schizophrenia and is seen in a variety of human tumor cell lines. Also, aberrant release of this protein is associated with the progression of Alzheimer's disease. [provided by RefSeq, Jul 2008]
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Gene Synonyms (COLL1, HH16, Hsema-I, Hsema-III, SEMA1, SEMAD, SEMAIII, SEMAL, SemD, coll-1, semaphorin-3A, collapsin 1, sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A, semaphorin D, semaphorin III, semaphorin L,)
- NCBI Gene ID:
10371
- Species:
Homo sapiens (Human)
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UNIPROT ID#>>Q14563
- View the NCBI Database
for this Gene »
Gene products are often involved in multiple pathways and networks within a living
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semaphorin 3A interacts with:
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