- Gene Overview
- Interaction Network
- Sequence Verification
FBXW10, F-box and WD repeat domain containing 10
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Members of the F-box protein family, such as FBXW10, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1; MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004 [PubMed 15520277]).[supplied by OMIM, Mar 2008]
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Gene Synonyms (Fbw10, HREP, SM25H2, SM2SH2, F-box/WD repeat-containing protein 10, F-box and WD-40 domain protein 10, testicular tissue protein Li 69, ubiquitin ligase specificity factor,)
- NCBI Gene ID:
10517
- Species:
Homo sapiens (Human)
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UNIPROT ID#>>Q5XX13
- View the NCBI Database
for this Gene »
Gene products are often involved in multiple pathways and networks within a living
cell. Learn more about other interacting partners.
F-box and WD repeat domain containing 10 interacts with:
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