MXD4, MAX dimerization protein 4

MXD4, MAX dimerization protein 4

• This gene is a member of the MAD gene family . The MAD genes encode basic helix-loop-helix-leucine zipper proteins that heterodimerize with MAX protein, forming a transcriptional repression complex. The MAD proteins compete for MAX binding with MYC, which heterodimerizes with MAX forming a transcriptional activation complex. Studies in rodents suggest that the MAD genes are tumor suppressors and contribute to the regulation of cell growth in differentiating tissues. [provided by RefSeq, Jul 2008]

• Gene Synonyms (MAD4, MST149, MSTP149, bHLHc12, max dimerization protein 4, Mad4 homolog, class C basic helix-loop-helix protein 12, max dimerizer 4, max-associated protein 4, max-interacting transcriptional repressor MAD4,)
• NCBI Gene ID: 10608
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q14582
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

MAX dimerization protein 4 interacts with:

• Max protein
  SIN3 transcription regulator family member A
  t-complex 10 like
  trafficking protein particle complex 11

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