SUGT1, SGT1 homolog, MIS12 kinetochore complex assembly cochaperone

SUGT1, SGT1 homolog, MIS12 kinetochore complex assembly cochaperone

• This gene encodes a highly conserved nuclear protein involved in kinetochore function and required for the G1/S and G2/M transitions. This protein interacts with heat shock protein 90. Alternative splicing results in multiple transcript variants. Pseudogenes for this gene have been defined on several different chromosomes. [provided by RefSeq, Mar 2016]

• Gene Synonyms (SGT1, protein SGT1 homolog, SGT1, suppressor of G2 allele of SKP1, putative 40-6-3 protein, suppressor of G2 allele of SKP1, S. cerevisiae, homolog of,)
• NCBI Gene ID: 10910
• Species: Homo sapiens (Human)
• UNIPROT ID#>>A8K7W3
  UNIPROT ID#>>B4DYC6
  UNIPROT ID#>>Q9Y2Z0
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

SGT1 homolog, MIS12 kinetochore complex assembly cochaperone interacts with:

• aldehyde dehydrogenase 1 family member L2
  autophagy and beclin 1 regulator 1
  BICD cargo adaptor 2
  calcyclin binding protein
  centromere protein H
  centrosomal protein 97
  chloride intracellular channel 4
  chromosome 11 open reading frame 58
  clusterin associated protein 1
  cysteine and histidine rich domain containing 1
  cysteine and histidine-rich domain (CHORD)-containing, zinc-binding protein 1
  DExD/H-box helicase 60
  DSN1 component of MIS12 kinetochore complex
  dynein light chain roadblock-type 1
  EvC ciliary complex subunit 2
  Fas associated factor 1
  F-box and leucine rich repeat protein 14
  FKBP prolyl isomerase 8
  histone deacetylase 11
  integrin beta 1 binding protein 2
  kelch like family member 18
  leucine rich repeat containing 10
  leucine rich repeat containing 39
  leucine rich repeat containing 40
  leucine rich repeat containing 42
  leucine rich repeat containing 57
  leucine rich repeat containing 8 VRAC subunit B
  leucine rich repeat protein 1
  leucine rich repeats and calponin homology domain containing 3
  MIS12 kinetochore complex component
  MKS transition zone complex subunit 1
  MYG1 exonuclease
  nephrocystin 4
  neuraminidase 4
  NIMA related kinase 8
  NLR family pyrin domain containing 2
  NLR family pyrin domain containing 3
  NLR family pyrin domain containing 4
  NSL1 component of MIS12 kinetochore complex
  nucleotide binding oligomerization domain containing 2
  par-6 family cell polarity regulator alpha
  PAX interacting protein 1
  peptidylprolyl isomerase like 3
  PH domain and leucine rich repeat protein phosphatase 1
  PH domain and leucine rich repeat protein phosphatase 2
  POC1 centriolar protein A
  polyamine modulated factor 1
  pyridoxamine 5'-phosphate oxidase
  RNA polymerase II associated protein 3
  selenophosphate synthetase 1
  Shoc2, leucine rich repeat scaffold protein
  SNW domain containing 1
  WD repeat domain 12
  WD repeat domain 76
  WD repeat domain 90

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.