SRSF8, serine and arginine rich splicing factor 8

SRSF8, serine and arginine rich splicing factor 8

• This gene encodes a member of a family of proteins containing a ribonucleoprotein (RNP)-type RNA binding motif and a carboxyl-terminal arginine-serine-rich (RS) domain. The encoded protein functions as a pre-mRNA splicing factor. There is a pseudogene for this gene on chromosome 7. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2013]

• Gene Synonyms (DSM-1, SFRS2B, SRP46, serine/arginine-rich splicing factor 8, SR splicing factor 8, pre-mRNA-splicing factor SRP46, splicing factor, arginine/serine-rich 2B, splicing factor, arginine/serine-rich, 46kD,)
• NCBI Gene ID: 10929
• Species: Homo sapiens (Human)
• UNIPROT ID#>>A0A024R3A8
  UNIPROT ID#>>Q9BRL6
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

serine and arginine rich splicing factor 8 interacts with:

• apolipoprotein B mRNA editing enzyme catalytic subunit 3D
  coiled-coil domain containing 88A
  immunoglobulin superfamily member 8
  interleukin 36 receptor antagonist
  keratin associated protein 12-2
  LUC7 like
  LUC7 like 2, pre-mRNA splicing factor
  MAP/microtubule affinity regulating kinase 2
  NKAP domain containing 1
  nuclear RNA export factor 2
  pleckstrin homology domain containing A4
  RAD18 E3 ubiquitin protein ligase
  serine and arginine-rich splicing factor 1
  Smad nuclear interacting protein 1
  splicing regulatory glutamic acid and lysine rich protein 1
  SUZ12 polycomb repressive complex 2 subunit
  transformer 2 alpha homolog
  tubulin, gamma 1
  zinc finger CCCH-type containing 18

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.