WIF1, WNT inhibitory factor 1

WIF1, WNT inhibitory factor 1

• The protein encoded by this gene functions to inhibit WNT proteins, which are extracellular signaling molecules that play a role in embryonic development. This protein contains a WNT inhibitory factor (WIF) domain and five epidermal growth factor (EGF)-like domains, and is thought to be involved in mesoderm segmentation. This gene functions as a tumor suppressor gene, and has been found to be epigenetically silenced in various cancers. [provided by RefSeq, Jun 2010]

• Gene Synonyms (wnt inhibitory factor 1, WIF-1,)
• NCBI Gene ID: 11197
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q9Y5W5
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

WNT inhibitory factor 1 interacts with:

• cysteine rich tail 1
  inducible T cell costimulator
  keratin associated protein 10-3
  keratin associated protein 10-8

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.