APOA5, apolipoprotein A5

APOA5, apolipoprotein A5

• The protein encoded by this gene is an apolipoprotein that plays an important role in regulating the plasma triglyceride levels, a major risk factor for coronary artery disease. It is a component of high density lipoprotein and is highly similar to a rat protein that is upregulated in response to liver injury. Mutations in this gene have been associated with hypertriglyceridemia and hyperlipoproteinemia type 5. This gene is located proximal to the apolipoprotein gene cluster on chromosome 11q23. Alternatively spliced transcript variants encoding the same protein have been identified. [provided by RefSeq, Oct 2009]

• Gene Synonyms (APOAV, RAP3, apolipoprotein A-V, apo-AV, apolipoprotein A-V precursor variant 3, regeneration-associated protein 3,)
• NCBI Gene ID: 116519
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q6Q788
  UNIPROT ID#>>A0A0B4RUS7
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

apolipoprotein A5 interacts with:

• CKLF like MARVEL transmembrane domain containing 3
  MORN repeat containing 4
  transmembrane protein 120B

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.