AGAP3, ArfGAP with GTPase domain, ankyrin repeat and PH domain 3

AGAP3, ArfGAP with GTPase domain, ankyrin repeat and PH domain 3

• This gene encodes an essential component of the N-methyl-D-aspartate (NMDA) receptor signaling complex which mediates long-term potentiation in synapses by linking activation of NMDA receptor to alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptor trafficking. The encoded protein contains an N-terminal GTPase-like domain, a pleckstrin homology domain, an ArfGAP domain and several C-terminal ankryn repeat domains. [provided by RefSeq, Apr 2017]

• Gene Synonyms (AGAP-3, CENTG3, CRAG, MRIP-1, cnt-g3, arf-GAP with GTPase, ANK repeat and PH domain-containing protein 3, CRAM-associated GTPase, CRMP (collapsin response mediator protein) associated, MR1-interacting protein, centaurin-gamma-3,)
• NCBI Gene ID: 116988
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q86ST5
  UNIPROT ID#>>Q96P47
  UNIPROT ID#>>D3DX07
  UNIPROT ID#>>C9J975
  UNIPROT ID#>>E7ESL9
  UNIPROT ID#>>Q86XV5
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

ArfGAP with GTPase domain, ankyrin repeat and PH domain 3 interacts with:

• folliculin
  G protein-coupled receptor 156

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.