TPH2, tryptophan hydroxylase 2

TPH2, tryptophan hydroxylase 2

• This gene encodes a member of the pterin-dependent aromatic acid hydroxylase family. The encoded protein catalyzes the first and rate limiting step in the biosynthesis of serotonin, an important hormone and neurotransmitter. Mutations in this gene may be associated with psychiatric diseases such as bipolar affective disorder and major depression. [provided by RefSeq, Feb 2016]

• Gene Synonyms (ADHD7, NTPH, tryptophan 5-hydroxylase 2, neuronal tryptophan hydroxylase, tryptophan 5-monooxygenase 2,)
• NCBI Gene ID: 121278
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q8IWU9
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

tryptophan hydroxylase 2 interacts with:

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.