EARS2, glutamyl-tRNA synthetase 2, mitochondrial

EARS2, glutamyl-tRNA synthetase 2, mitochondrial

• This gene encodes a member of the class I family of aminoacyl-tRNA synthetases. These enzymes play a critical role in protein biosynthesis by charging tRNAs with their cognate amino acids. This protein is encoded by the nuclear genome but is likely to be imported to the mitochondrion where it is thought to catalyze the ligation of glutamate to tRNA molecules. Mutations in this gene have been associated with combined oxidative phosphorylation deficiency 12 (COXPD12). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2015]

• Gene Synonyms (COXPD12, MSE1, gluRS, mtGlnRS, probable glutamate--tRNA ligase, mitochondrial, glutamate tRNA ligase 2, mitochondrial, glutamate--tRNA ligase, probable glutamyl-tRNA synthetase, mitochondrial,)
• NCBI Gene ID: 124454
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q5JPH6
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

glutamyl-tRNA synthetase 2, mitochondrial interacts with:

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