Cry2, cryptochrome 2 (photolyase-like)

Cry2, cryptochrome 2 (photolyase-like)

• This gene encodes a flavin adenine dinucleotide-binding protein that is a key component of the circadian core oscillator complex, which regulates the circadian clock. This gene is upregulated by Clock/Arntl heterodimers but then represses this upregulation in a feedback loop using Per/Cry heterodimers to interact with Clock/Arntl. Polymorphisms in this gene have been associated with altered sleep patterns. The encoded protein is widely conserved across plants and animals. [provided by RefSeq, Feb 2014]

• (No alternate names found)
• NCBI Gene ID: 12953
• Species: Mus musculus (Mouse)
• UNIPROT ID#>>Q9R194
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

cryptochrome 2 (photolyase-like) interacts with:

• F-box and leucine rich repeat protein 3
  F-box and leucine-rich repeat protein 3
  karyopherin (importin) alpha 2
  karyopherin (importin) alpha 4
  karyopherin (importin) alpha 6
  period circadian clock 1
  period circadian clock 2
  period circadian clock 3
  ubiquitin specific peptidase 2

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.