FRMPD2, FERM and PDZ domain containing 2

FRMPD2, FERM and PDZ domain containing 2

• This gene encodes a peripheral membrane protein and is located in a region of chromosome 10q that contains a segmental duplication. This copy of the gene is full-length and is in the telomeric duplicated region. Two other more centromerically proximal copies of the gene are partial and may represent pseudogenes. This full-length gene appears to function in the establishment and maintenance of cell polarization. The protein is recruited to cell-cell junctions in an E-cadherin-dependent manner, and is selectively localized at the basolateral membrane in polarized epithelial cells. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2009]

• Gene Synonyms (PDZD5C, PDZK4, PDZK5C, FERM and PDZ domain-containing protein 2, PDZ domain containing 5C, PDZ domain-containing protein 4,)
• NCBI Gene ID: 143162
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q68DX3
  UNIPROT ID#>>B4E1N9
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

FERM and PDZ domain containing 2 interacts with:

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.