BCDIN3D, BCDIN3 domain containing RNA methyltransferase

BCDIN3D, BCDIN3 domain containing RNA methyltransferase

• This gene encodes an RNA methyltransferase which belongs to the rossmann fold methyltransferase family, and serves as a 5'-methylphosphate capping enzyme that is specific for cytoplasmic histidyl tRNA. The encoded protein contains an S-adenosylmethionine binding domain and uses the methyl group donor, S-adenosylmethionine. This gene is overexpressed in breast cancer cells, and is related to the tumorigenic phenotype and poor prognosis of breast cancer. The encoded protein is thought to promote the cellular invasion of breast cancer cells, by downregulating the expression of tumor suppressor miRNAs through the dimethylation of the 5-monophosphate of the corresponding precursor miRNAs. [provided by RefSeq, Apr 2017]

• Gene Synonyms (RNA 5'-monophosphate methyltransferase, BCDIN3 domain containing RNA methyltransfease, BCDIN3 domain-containing protein, pre-miRNA 5'-monophosphate methyltransferase, probable methyltransferase BCDIN3D,)
• NCBI Gene ID: 144233
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q7Z5W3
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

BCDIN3 domain containing RNA methyltransferase interacts with:

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