PIK3R6, phosphoinositide-3-kinase regulatory subunit 6

PIK3R6, phosphoinositide-3-kinase regulatory subunit 6

• Phosphoinositide 3-kinase gamma is a lipid kinase that produces the lipid second messenger phosphatidylinositol 3,4,5-trisphosphate. The kinase is composed of a catalytic subunit and one of several regulatory subunits, and is chiefly activated by G protein-coupled receptors. This gene encodes a regulatory subunit, and is distantly related to the phosphoinositide-3-kinase, regulatory subunit 5 gene which is located adjacent to this gene on chromosome 7. The orthologous protein in the mouse binds to both the catalytic subunit and to G(beta/gamma), and mediates activation of the kinase subunit downstream of G protein-coupled receptors. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2014]

• Gene Synonyms (C17orf38, HsT41028, p84 PIKAP, p87(PIKAP), p87PIKAP, phosphoinositide 3-kinase regulatory subunit 6, PI3Kgamma adapter protein of 87 kDa, p84 PI3K adapter protein, p87 phosphoinositide 3-kinase gamma (PI3Kg) adapter protein,)
• NCBI Gene ID: 146850
• Species: Homo sapiens (Human)
• UNIPROT ID#>>B3KRK9
  UNIPROT ID#>>Q5UE93
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

phosphoinositide-3-kinase regulatory subunit 6 interacts with:

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