ZNF420, zinc finger protein 420

ZNF420, zinc finger protein 420

• The protein encoded by this gene is a KRAB-type zinc finger protein that negatively-regulates p53-mediated apoptosis. Under stress conditions, the encoded protein is phosphorylated by ATM and dissociates from p53, which activates p53 and initiates apoptosis. [provided by RefSeq, Jul 2016]

• Gene Synonyms (APAK, zinc finger protein 420, ATM and p53-associated KZNF protein,)
• NCBI Gene ID: 147923
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q8TAQ5
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

zinc finger protein 420 interacts with:

• cytochrome P450 family 4 subfamily V member 2
  keratin associated protein 10-7

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.