TOR1AIP2, torsin 1A interacting protein 2

TOR1AIP2, torsin 1A interacting protein 2

• One of the two protein isoforms encoded by this gene is a type II integral membrane protein found in the endoplasmic reticulum (ER). The encoded protein is a cofactor for the ATPase TorsinA, regulating the amount of TorsinA present in the ER compared to that found in the nuclear envelope. Defects in this protein are a cause of early onset primary dystonia, a neuromuscular disease. The other isoform encoded by this gene is an interferon alpha responsive protein whose cellular role has yet to be determined. [provided by RefSeq, Mar 2017]

• Gene Synonyms (torsin-1A-interacting protein 2, interferon alpha responsive protein, 15 kDa interferon-responsive protein, interferon responsive gene 15, lumenal domain like LAP1, torsin A interacting protein 2, IFRG15, LULL1, NET9,)
• NCBI Gene ID: 163590
• Species: Homo sapiens (Human)
• UNIPROT ID#>>A0A024R957
  UNIPROT ID#>>Q8NFQ8
  UNIPROT ID#>>Q9H496
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

torsin 1A interacting protein 2 interacts with:

• RAB15, member RAS oncogene family
  solute carrier family 25 member 30
  tubulin beta 8 class VIII

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.