EPB42, erythrocyte membrane protein band 4.2

EPB42, erythrocyte membrane protein band 4.2

• Erythrocyte membrane protein band 4.2 is an ATP-binding protein which may regulate the association of protein 3 with ankyrin. It probably has a role in erythrocyte shape and mechanical property regulation. Mutations in the EPB42 gene are associated with recessive spherocytic elliptocytosis and recessively transmitted hereditary hemolytic anemia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

• Gene Synonyms (PA, SPH5, erythrocyte membrane protein band 4.2, P4.2, erythrocyte protein 4.2, erythrocyte surface protein band 4.2,)
• NCBI Gene ID: 2038
• Species: Homo sapiens (Human)
• UNIPROT ID#>>P16452
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

erythrocyte membrane protein band 4.2 interacts with:

• biogenesis of lysosomal organelles complex 1 subunit 4
  dematin actin binding protein
  heat shock protein family A (Hsp70) member 8
  KRAS proto-oncogene, GTPase
  La ribonucleoprotein 7, transcriptional regulator
  serine peptidase inhibitor Kazal type 7
  solute carrier family 4 member 1 (Diego blood group)
  solute carrier family 4 member 2
  solute carrier family 4 member 7
  sorting nexin 6
  spectrin alpha, non-erythrocytic 1
  syntaxin 12

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