Agap2, ArfGAP with GTPase domain, ankyrin repeat and PH domain 2

Agap2, ArfGAP with GTPase domain, ankyrin repeat and PH domain 2

• The protein encoded by this gene is a member of the centaurin GTPase family. This gene product regulates the activity of multiple kinases, including PI3K. Reduced expression of this gene results in multiple defects, including neural deficiencies, while increased expression of this gene has been observed in some tumors. Alternative splicing results in multiple protein isoforms. [provided by RefSeq, Jul 2014]

• (No alternate names found)
• NCBI Gene ID: 216439
• Species: Mus musculus (Mouse)
• UNIPROT ID#>>Q3UHD9
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

ArfGAP with GTPase domain, ankyrin repeat and PH domain 2 interacts with:

• adenylate kinase 5
  centrosomal protein 170B
  connector enhancer of kinase suppressor of Ras 2
  DLG associated protein 1
  DLG associated protein 2
  DLG associated protein 3
  DLG associated protein 4
  dynein cytoplasmic 1 light intermediate chain 1
  gelsolin
  gephyrin
  GIT ArfGAP 1
  internexin neuronal intermediate filament protein, alpha
  IQ motif and Sec7 domain 1
  IQ motif and Sec7 domain 2
  IQ motif and Sec7 domain 3
  IQ motif containing GTPase activating protein 2
  kalirin, RhoGEF kinase
  leucine rich repeat containing 7
  leucine zipper protein 1
  neuroligin 3
  neuronal cell adhesion molecule
  PEAK1 related kinase activating pseudokinase 1
  phosphatase and actin regulator 1
  phosphatidylinositol-4-phosphate 5-kinase-like 1
  potassium channel tetramerisation domain containing 16
  protein arginine N-methyltransferase 8
  protein phosphatase 1, regulatory subunit 9A
  protein phosphatase 1, regulatory subunit 9B
  protein phosphatase 1E (PP2C domain containing)
  protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1
  protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 2
  RAS protein activator like 2
  Rho GTPase activating protein 39
  septin 7
  SH3 and multiple ankyrin repeat domains 1
  SLIT-ROBO Rho GTPase activating protein 3
  sorbin and SH3 domain containing 2
  striatin, calmodulin binding protein
  suppressor of glucose, autophagy associated 1
  synaptic Ras GTPase activating protein 1 homolog (rat)
  TRAF2 and NCK interacting kinase
  triple functional domain (PTPRF interacting)

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.