ACSL1, acyl-CoA synthetase long chain family member 1

ACSL1, acyl-CoA synthetase long chain family member 1

• The protein encoded by this gene is an isozyme of the long-chain fatty-acid-coenzyme A ligase family. Although differing in substrate specificity, subcellular localization, and tissue distribution, all isozymes of this family convert free long-chain fatty acids into fatty acyl-CoA esters, and thereby play a key role in lipid biosynthesis and fatty acid degradation. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2013]

• Gene Synonyms (ACS1, FACL1, FACL2, LACS, LACS1, LACS2, long-chain-fatty-acid--CoA ligase 1, LACS 1, LACS 2, acyl-CoA synthetase 1, arachidonate--CoA ligase, fatty-acid-Coenzyme A ligase, long-chain 1, fatty-acid-Coenzyme A ligase, long-chain 2, lignoceroyl-CoA synthase, long-chain acyl-CoA synthetase 1, long-chain acyl-CoA synthetase 2, long-chain fatty acid-CoA ligase 2, long-chain fatty-acid-coenzyme A ligase 1, palmitoyl-CoA ligase 1, palmitoyl-CoA ligase 2, paltimoyl-CoA ligase 1, phytanate--CoA ligase,)
• NCBI Gene ID: 2180
• Species: Homo sapiens (Human)
• UNIPROT ID#>>E7EPM6
  UNIPROT ID#>>A8K9T3
  UNIPROT ID#>>B4E0R0
  UNIPROT ID#>>P33121
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

acyl-CoA synthetase long chain family member 1 interacts with:

• chromosome 15 open reading frame 48
  coenzyme Q9
  CTD phosphatase subunit 1
  egl-9 family hypoxia inducible factor 3
  MYC proto-oncogene, bHLH transcription factor
  NDUFA4 mitochondrial complex associated
  neurotrophic receptor tyrosine kinase 1
  nuclear receptor subfamily 3 group C member 2
  parkin RBR E3 ubiquitin protein ligase
  tripartite motif containing 25
  WW domain containing oxidoreductase

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.