CHSY1, chondroitin sulfate synthase 1

CHSY1, chondroitin sulfate synthase 1

• This gene encodes a member of the chondroitin N-acetylgalactosaminyltransferase family. These enzymes possess dual glucuronyltransferase and galactosaminyltransferase activity and play critical roles in the biosynthesis of chondroitin sulfate, a glycosaminoglycan involved in many biological processes including cell proliferation and morphogenesis. Decreased expression of this gene may play a role in colorectal cancer, and mutations in this gene are a cause of temtamy preaxial brachydactyly syndrome. [provided by RefSeq, Dec 2011]

• Gene Synonyms (CHSY, CSS1, ChSy-1, TPBS, chondroitin sulfate synthase 1, N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase 1, N-acetylgalactosaminyltransferase II, carbohydrate synthase 1, chondroitin glucuronyltransferase 1, chondroitin glucuronyltransferase II, chondroitin synthase 1, glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase 1,)
• NCBI Gene ID: 22856
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q86X52
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

chondroitin sulfate synthase 1 interacts with:

• chondroitin sulfate N-acetylgalactosaminyltransferase 2
  chondroitin sulfate synthase 3
  golgi transport 1B
  limb development membrane protein 1 like
  solute carrier family 39 member 12
  solute carrier family 39 member 4
  stromal cell derived factor 4
  vir like m6A methyltransferase associated

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.