RIMS1, regulating synaptic membrane exocytosis 1

RIMS1, regulating synaptic membrane exocytosis 1

• The protein encoded by this gene is a RAS gene superfamily member that regulates synaptic vesicle exocytosis. This gene also plays a role in the regulation of voltage-gated calcium channels during neurotransmitter and insulin release. Mutations have suggested a role cognition and have been identified as the cause of cone-rod dystrophy type 7. Multiple transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Mar 2012]

• Gene Synonyms (CORD7, RAB3IP2, RIM, RIM1, regulating synaptic membrane exocytosis protein 1, RAB3-interacting protein 2, rab-3-interacting protein 2, rab3-interacting molecule 1,)
• NCBI Gene ID: 22999
• Species: Homo sapiens (Human)
• UNIPROT ID#>>B7Z9Z3
  UNIPROT ID#>>Q86UR5
  UNIPROT ID#>>Q3ZCW0
  UNIPROT ID#>>B7Z7W2
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

regulating synaptic membrane exocytosis 1 interacts with:

• centrosomal protein 135
  charged multivesicular body protein 4B
  ELKS/RAB6-interacting/CAST family member 1
  ELKS/RAB6-interacting/CAST family member 2
  katanin p60 (ATPase-containing) subunit A1
  leucine rich repeat kinase 1
  RAB26, member RAS oncogene family
  RAB37, member RAS oncogene family
  shugoshin 1
  striatin, calmodulin binding protein 3
  transmembrane p24 trafficking protein 10

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.