SYNE2, spectrin repeat containing nuclear envelope protein 2

SYNE2, spectrin repeat containing nuclear envelope protein 2

• The protein encoded by this gene is a nuclear outer membrane protein that binds cytoplasmic F-actin. This binding tethers the nucleus to the cytoskeleton and aids in the maintenance of the structural integrity of the nucleus. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009]

• Gene Synonyms (EDMD5, KASH2, NUA, NUANCE, Nesp2, Nesprin-2, SYNE-2, TROPH, nesprin-2, KASH domain-containing protein 2, nesprin 2, nuclear envelope spectrin repeat protein 2, nucleus and actin connecting element protein, polytrophin, spectrin repeat containing, nuclear envelope 2, synaptic nuclear envelope protein 2, synaptic nuclei expressed gene 2,)
• NCBI Gene ID: 23224
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q6MZP0
  UNIPROT ID#>>Q8WXH0
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

spectrin repeat containing nuclear envelope protein 2 interacts with:

• charged multivesicular body protein 4C
  CTD nuclear envelope phosphatase 1
  cullin 1
  hes related family bHLH transcription factor with YRPW motif 1
  histone deacetylase 11
  hypoxia inducible factor 1 subunit alpha inhibitor
  mitogen-activated protein kinase 8 interacting protein 2
  MKS transition zone complex subunit 1
  MORC family CW-type zinc finger 3
  obscurin like cytoskeletal adaptor 1
  OTU deubiquitinase with linear linkage specificity like
  potassium channel tetramerisation domain containing 5
  protein arginine methyltransferase 8
  rhomboid domain containing 1
  ribonuclease H2 subunit B
  Sad1 and UNC84 domain containing 1
  Sad1 and UNC84 domain containing 2
  SAM and SH3 domain containing 1
  sirtuin 7
  SLX4 interacting protein
  TBC1 domain family member 16
  transmembrane protein 67
  vir like m6A methyltransferase associated

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.