FBXO46, F-box protein 46

FBXO46, F-box protein 46

• Members of the F-box protein family, such as FBXO46, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1; MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004 [PubMed 15520277]).[supplied by OMIM, Mar 2008]

• Gene Synonyms (F-box only protein 46, 20D7-FC4, FBXO34L, Fbx46,)
• NCBI Gene ID: 23403
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q6PJ61
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

F-box protein 46 interacts with:

• arrestin, beta 2
  fibronectin type III and SPRY domain containing 1
  leucine rich repeat and fibronectin type III domain containing 4
  myosin XIX
  myosin XVIIIA
  nexilin F-actin binding protein
  solute carrier family 25 member 41
  tropomodulin 3

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.