Ago1, argonaute RISC catalytic subunit 1

Ago1, argonaute RISC catalytic subunit 1

• This gene encodes a member of the argonaute family of proteins, which associate with small RNAs and have important roles in RNA interference (RNAi) and RNA silencing. This protein binds to microRNAs (miRNAs) or small interfering RNAs (siRNAs) and represses translation of mRNAs that are complementary to them. It is also involved in transcriptional gene silencing (TGS) of promoter regions that are complementary to bound short antigene RNAs (agRNAs), as well as in the degradation of miRNA-bound mRNA targets. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. A recent study showed this gene to be an authentic stop codon readthrough target, and that its mRNA could give rise to an additional C-terminally extended isoform by use of an alternative in-frame translation termination codon. [provided by RefSeq, Nov 2015]

• (No alternate names found)
• NCBI Gene ID: 236511
• Species: Mus musculus (Mouse)
• UNIPROT ID#>>Q8BJP2
  UNIPROT ID#>>Q8CJG1
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

argonaute RISC catalytic subunit 1 interacts with:

• argonaute RISC catalytic subunit 2

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