ATP2C1, ATPase secretory pathway Ca2+ transporting 1

ATP2C1, ATPase secretory pathway Ca2+ transporting 1

• The protein encoded by this gene belongs to the family of P-type cation transport ATPases. This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium ions. Defects in this gene cause Hailey-Hailey disease, an autosomal dominant disorder. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Aug 2011]

• Gene Synonyms (ATP2C1A, BCPM, HHD, PMR1, SPCA1, hSPCA1, calcium-transporting ATPase type 2C member 1, ATP-dependent Ca(2+) pump PMR1, ATPase 2C1, ATPase, Ca(2+)-sequestering, ATPase, Ca++ transporting, type 2C, member 1, HUSSY-28, secretory pathway Ca2+/Mn2+ ATPase 1,)
• NCBI Gene ID: 27032
• Species: Homo sapiens (Human)
• UNIPROT ID#>>B4E295
  UNIPROT ID#>>P98194
  UNIPROT ID#>>B4E2Q0
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

ATPase secretory pathway Ca2+ transporting 1 interacts with:

• 2-oxoglutarate and iron dependent oxygenase domain containing 3
  golgi transport 1B
  limb development membrane protein 1 like
  OTU deubiquitinase with linear linkage specificity
  OTU deubiquitinase with linear linkage specificity like
  pleckstrin homology domain containing A4
  regulator of microtubule dynamics 3
  transmembrane p24 trafficking protein 2
  transmembrane protein 165
  transmembrane protein 17
  transmembrane protein 231
  USO1 vesicle docking factor

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.