GJB3, gap junction protein beta 3

GJB3, gap junction protein beta 3

• This gene is a member of the connexin gene family. The encoded protein is a component of gap junctions, which are composed of arrays of intercellular channels that provide a route for the diffusion of low molecular weight materials from cell to cell. Mutations in this gene can cause non-syndromic deafness or erythrokeratodermia variabilis, a skin disorder. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq, Jul 2008]

• Gene Synonyms (gap junction beta-3 protein, connexin 31, gap junction protein, beta 3, 31kDa, CX31, DFNA2, DFNA2B, EKV, EKVP1,)
• NCBI Gene ID: 2707
• Species: Homo sapiens (Human)
• UNIPROT ID#>>O75712
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

gap junction protein beta 3 interacts with:

• butyrophilin subfamily 2 member A2
  consortin, connexin sorting protein
  GTPase, IMAP family member 5
  insulin like growth factor binding protein 5
  LHFPL tetraspan subfamily member 5
  linker for activation of T cells
  major facilitator superfamily domain containing 11
  reprimo, TP53 dependent G2 arrest mediator homolog
  stress associated endoplasmic reticulum protein 1
  tight junction protein 1
  trafficking regulator of GLUT4 (SLC2A4) 1
  transmembrane and ubiquitin like domain containing 2
  transmembrane protein 97

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.