EIF2AK1, eukaryotic translation initiation factor 2 alpha kinase 1

EIF2AK1, eukaryotic translation initiation factor 2 alpha kinase 1

• The protein encoded by this gene acts at the level of translation initiation to downregulate protein synthesis in response to stress. The encoded protein is a kinase that can be inactivated by hemin. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008]

• Gene Synonyms (eukaryotic translation initiation factor 2-alpha kinase 1, heme regulated initiation factor 2 alpha kinase, heme sensitive initiation factor 2a kinase, heme-controlled repressor, heme-regulated eukaryotic initiation factor eIF-2-alpha kinase, heme-regulated inhibitor, heme-regulated repressor, hemin-sensitive initiation factor 2-alpha kinase, HCR, HRI, LEMSPAD, hHRI,)
• NCBI Gene ID: 27102
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q9BQI3
  UNIPROT ID#>>A0A024QZU1
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

eukaryotic translation initiation factor 2 alpha kinase 1 interacts with:

• ELL associated factor 1
  eukaryotic translation initiation factor 2 alpha kinase 1
  nuclear assembly factor 1 ribonucleoprotein

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.