PDLIM3, PDZ and LIM domain 3

PDLIM3, PDZ and LIM domain 3

• The protein encoded by this gene contains a PDZ domain and a LIM domain, indicating that it may be involved in cytoskeletal assembly. In support of this, the encoded protein has been shown to bind the spectrin-like repeats of alpha-actinin-2 and to colocalize with alpha-actinin-2 at the Z lines of skeletal muscle. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. Aberrant alternative splicing of this gene may play a role in myotonic dystrophy. [provided by RefSeq, Apr 2012]

• Gene Synonyms (PDZ and LIM domain protein 3, alpha-actinin-2-associated LIM protein, enigma homolog, ALP,)
• NCBI Gene ID: 27295
• Species: Homo sapiens (Human)
• UNIPROT ID#>>A0A0A0MQY0
  UNIPROT ID#>>Q53GG5
  UNIPROT ID#>>A0A087WYF8
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

PDZ and LIM domain 3 interacts with:

• ras homolog family member U

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.