SUMF1, sulfatase modifying factor 1

SUMF1, sulfatase modifying factor 1

• This gene encodes an enzyme that catalyzes the hydrolysis of sulfate esters by oxidizing a cysteine residue in the substrate sulfatase to an active site 3-oxoalanine residue, which is also known as C-alpha-formylglycine. Mutations in this gene cause multiple sulfatase deficiency, a lysosomal storage disorder. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2009]

• Gene Synonyms (formylglycine-generating enzyme, C-alpha-formylglycine-generating enzyme 1, FGly-generating enzyme, AAPA3037, FGE, UNQ3037,)
• NCBI Gene ID: 285362
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q8NBK3
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

sulfatase modifying factor 1 interacts with:

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