EEF2K, eukaryotic elongation factor 2 kinase

EEF2K, eukaryotic elongation factor 2 kinase

• This gene encodes a highly conserved protein kinase in the calmodulin-mediated signaling pathway that links activation of cell surface receptors to cell division. This kinase is involved in the regulation of protein synthesis. It phosphorylates eukaryotic elongation factor 2 (EEF2) and thus inhibits the EEF2 function. The activity of this kinase is increased in many cancers and may be a valid target for anti-cancer treatment. [provided by RefSeq, Jul 2008]

• Gene Synonyms (eukaryotic elongation factor 2 kinase, alternative protein EEF2K, calcium/calmodulin-dependent eukaryotic elongation factor-2 kinase, calmodulin-dependent protein kinase III, eEF-2 kinase, elongation factor-2 kinase, eukaroytic elongation factor 2 kinase, CaMKIII, HSU93850, eEF-2K,)
• NCBI Gene ID: 29904
• Species: Homo sapiens (Human)
• UNIPROT ID#>>O00418
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

eukaryotic elongation factor 2 kinase interacts with:

• dihydrouridine synthase 3 like
  dipeptidyl peptidase 9
  O-sialoglycoprotein endopeptidase
  pantothenate kinase 4 (inactive)
  TP53 regulating kinase
  tRNA-histidine guanylyltransferase 1 like

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.