EVX2, even-skipped homeobox 2

EVX2, even-skipped homeobox 2

• This gene is located at the 5' end of the HOXD gene cluster on chromosome 2. The encoded protein is a homeobox transcription factor that is related to the protein encoded by the Drosophila even-skipped (eve) gene, a member of the pair-rule class of segmentation genes. A 117 kb microdeletion at the 5' end of the HOXD gene cluster, which includes this gene and the HOXD9-HOXD13 genes, causes synpolydactyly, a dominantly inherited disease resulting in limb malformation. [provided by RefSeq, Sep 2009]

• Gene Synonyms (EVX-2, homeobox even-skipped homolog protein 2, eve, even-skipped homeo box homolog 2, even-skipped homeo box 2 (homolog of Drosophila eve),)
• NCBI Gene ID: 344191
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q03828
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

even-skipped homeobox 2 interacts with:

• BPI fold containing family B member 3
  inter-alpha-trypsin inhibitor heavy chain family member 6

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.