LTBP3, latent transforming growth factor beta binding protein 3

LTBP3, latent transforming growth factor beta binding protein 3

• The protein encoded by this gene forms a complex with transforming growth factor beta (TGF-beta) proteins and may be involved in their subcellular localization. Activation of this complex requires removal of the encoded binding protein. This protein also may play a structural role in the extracellular matrix. Three transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Jan 2010]

• Gene Synonyms (DASS, GPHYSD3, LTBP-3, LTBP2, STHAG6, pp6425, latent-transforming growth factor beta-binding protein 3, latent TGF beta binding protein 3,)
• NCBI Gene ID: 4054
• Species: Homo sapiens (Human)
• UNIPROT ID#>>B9EG76
  UNIPROT ID#>>Q8WYU6
  UNIPROT ID#>>Q9NS15
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

latent transforming growth factor beta binding protein 3 interacts with:

• DnaJ heat shock protein family (Hsp40) member C10
  F-box protein 6
  golgi reassembly stacking protein 2
  pellino E3 ubiquitin protein ligase family member 2
  phosphoinositide-3-kinase regulatory subunit 2
  pre-mRNA processing factor 40 homolog A
  Rac family small GTPase 1
  transforming growth factor beta 1
  transforming growth factor beta 2
  transforming growth factor beta 3

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.