PNPLA8, patatin like phospholipase domain containing 8

PNPLA8, patatin like phospholipase domain containing 8

• This gene encodes a member of the patatin-like phospholipase domain containing protein family. Members of this family are phospholipases which catalyze the cleavage of fatty acids from membrane phospholipids. The product of this gene is a calcium-independent phospholipase. Mutations in this gene have been associated with mitochondrial myopathy with lactic acidosis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2015]

• Gene Synonyms (calcium-independent phospholipase A2-gamma, intracellular membrane-associated calcium-independent phospholipase A2 gamma, membrane-associated calcium-independent phospholipase A2 gamma, IPLA2-2, IPLA2G, MMLA, PNPLA-gamma, iPLA2gamma,)
• NCBI Gene ID: 50640
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q9NP80
  UNIPROT ID#>>A0A024R746
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

patatin like phospholipase domain containing 8 interacts with:

• small glutamine rich tetratricopeptide repeat containing beta

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.