ARHGEF4, Rho guanine nucleotide exchange factor 4

ARHGEF4, Rho guanine nucleotide exchange factor 4

• Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. The protein encoded by this gene may form complex with G proteins and stimulate Rho-dependent signals. Multiple alternatively spliced transcript variants encoding different isoforms have been found, but the full-length nature of some variants has not been determined. [provided by RefSeq, Jun 2013]

• Gene Synonyms (rho guanine nucleotide exchange factor 4, APC-stimulated guanine nucleotide exchange factor 1, Rho guanine nucleotide exchange factor (GEF) 4, ASEF, ASEF1, GEF4, SMIM39, STM6,)
• NCBI Gene ID: 50649
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q9NTG0
  UNIPROT ID#>>Q9NR80
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

Rho guanine nucleotide exchange factor 4 interacts with:

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.