ATL1, atlastin GTPase 1

ATL1, atlastin GTPase 1

• The protein encoded by this gene is a GTPase and a Golgi body transmembrane protein. The encoded protein can form a homotetramer and has been shown to interact with spastin and with mitogen-activated protein kinase kinase kinase kinase 4. This protein may be involved in axonal maintenance as evidenced by the fact that defects in this gene are a cause of spastic paraplegia type 3. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

• Gene Synonyms (atlastin-1, GBP-3, GTP-binding protein 3, brain-specific GTP-binding protein, guanine nucleotide-binding protein 3, guanylate-binding protein 3, hGBP3, spastic paraplegia 3 protein A, AD-FSP, FSP1, GBP3, HSN1D, SPG3, SPG3A, atlastin1,)
• NCBI Gene ID: 51062
• Species: Homo sapiens (Human)
• UNIPROT ID#>>A0A0S2Z5A2
  UNIPROT ID#>>Q8WXF7
  UNIPROT ID#>>Q53F53
  UNIPROT ID#>>A0A0S2Z5B0
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

atlastin GTPase 1 interacts with:

• OTU deubiquitinase with linear linkage specificity like
  pleckstrin homology domain containing A4
  rhomboid domain containing 1

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.