CRYL1, crystallin lambda 1

CRYL1, crystallin lambda 1

• The uronate cycle functions as an alternative glucose metabolic pathway, accounting for about 5% of daily glucose catabolism. The product of this gene catalyzes the dehydrogenation of L-gulonate into dehydro-L-gulonate in the uronate cycle. The enzyme requires NAD(H) as a coenzyme, and is inhibited by inorganic phosphate. A similar gene in the rabbit is thought to serve a structural role in the lens of the eye. [provided by RefSeq, Jul 2008]

• Gene Synonyms (lambda-crystallin homolog, L-gulonate 3-dehydrogenase, crystallin, lamda 1, epididymis luminal protein 30, testicular tissue protein Li 44, GDH, HEL30, gul3DH, lambda-CRY,)
• NCBI Gene ID: 51084
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q9Y2S2
  UNIPROT ID#>>V9HWG2
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

crystallin lambda 1 interacts with:

• anaphase promoting complex subunit 1
  anaphase promoting complex subunit 5
  BRCA1 interacting protein C-terminal helicase 1
  chromosome 5 open reading frame 34
  dynein cytoplasmic 2 heavy chain 1
  eukaryotic translation initiation factor 2 alpha kinase 4
  HAUS augmin like complex subunit 3
  hook microtubule tethering protein 1
  intraflagellar transport 122
  myosin light chain 12B
  myosin VC
  SMG8 nonsense mediated mRNA decay factor
  SPG11 vesicle trafficking associated, spatacsin
  TLC domain containing 3A
  tripartite motif containing 65
  ubiquitin specific peptidase 54
  WD repeat containing antisense to TP53
  WD repeat domain 59

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.