PRKAG2, protein kinase AMP-activated non-catalytic subunit gamma 2

PRKAG2, protein kinase AMP-activated non-catalytic subunit gamma 2

• AMP-activated protein kinase (AMPK) is a heterotrimeric protein composed of a catalytic alpha subunit, a noncatalytic beta subunit, and a noncatalytic regulatory gamma subunit. Various forms of each of these subunits exist, encoded by different genes. AMPK is an important energy-sensing enzyme that monitors cellular energy status and functions by inactivating key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This gene is a member of the AMPK gamma subunit family. Mutations in this gene have been associated with Wolff-Parkinson-White syndrome, familial hypertrophic cardiomyopathy, and glycogen storage disease of the heart. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jan 2015]

• Gene Synonyms (5'-AMP-activated protein kinase subunit gamma-2, AMPK subunit gamma-2, epididymis secretory sperm binding protein, protein kinase, AMP-activated, gamma 2 non-catalytic subunit, AAKG, AAKG2, CMH6, H91620p, WPWS,)
• NCBI Gene ID: 51422
• Species: Homo sapiens (Human)
• UNIPROT ID#>>B7Z6X8
  UNIPROT ID#>>A0A090N8Q6
  UNIPROT ID#>>Q9UGJ0
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

protein kinase AMP-activated non-catalytic subunit gamma 2 interacts with:

• DNA cross-link repair 1C
  microtubule associated protein 1 light chain 3 alpha
  stromal interaction molecule 2
  WD repeat domain 83

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.