UIMC1, ubiquitin interaction motif containing 1

UIMC1, ubiquitin interaction motif containing 1

• This gene encodes a nuclear protein that interacts with Brca1 (breast cancer 1) in a complex to recognize and repair DNA lesions. This protein binds ubiquitinated lysine 63 of histone H2A and H2AX. This protein may also function as a repressor of transcription. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015]

• Gene Synonyms (BRCA1-A complex subunit RAP80, receptor-associated protein 80, retinoid X receptor-interacting protein 110, RAP80, X2HRIP110,)
• NCBI Gene ID: 51720
• Species: Homo sapiens (Human)
• UNIPROT ID#>>A0A024R7R0
  UNIPROT ID#>>Q96RL1
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

ubiquitin interaction motif containing 1 interacts with:

• abraxas 1, BRCA1 A complex subunit
  angiomotin
  ATPase phospholipid transporting 8A2
  BRCA1/BRCA2-containing complex subunit 3
  centrosomal protein 57
  COMM domain containing 8
  dpy-30 histone methyltransferase complex regulatory subunit
  ETAA1 activator of ATR kinase
  INO80 complex subunit B
  lin-7 homolog C, crumbs cell polarity complex component
  pyrroline-5-carboxylate reductase 3
  ribosomal oxygenase 2
  tankyrase 2
  threonine synthase like 1
  WD repeat domain 48

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.