NUDT9, nudix hydrolase 9

NUDT9, nudix hydrolase 9

• The protein encoded by this gene belongs to the Nudix hydrolase family. Nudix boxes are found in a family of diverse enzymes that catalyze the hydrolysis of nucleoside diphosphate derivatives. This enzyme is an ADP-ribose pyrophosphatase that catalyzes the hydrolysis of ADP-ribose to AMP and ribose-5-P. It requires divalent metal ions and an intact Nudix motif for enzymatic activity. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]

• Gene Synonyms (ADP-ribose pyrophosphatase, mitochondrial, ADP-ribose diphosphatase, ADP-ribose phosphohydrolase, ADP-ribose pyrosphosphatase NUDT9, ADPR-PPase, adenosine diphosphoribose pyrophosphatase, nucleoside diphosphate linked moiety X-type motif 9, nudix (nucleoside diphosphate linked moiety X)-type motif 9, NUDT10,)
• NCBI Gene ID: 53343
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q8NG26
  UNIPROT ID#>>Q9BW91
  UNIPROT ID#>>A0A024RDI6
  UNIPROT ID#>>Q96KB3
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

nudix hydrolase 9 interacts with:

• tripartite motif containing 11
  WD repeat domain 5B

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.